Parasite Eve Day 1 Walkthrough
The game begins with you arriving in a vehicle outside of Carnegie Hall in New York City. You'll be asked to name Aya (the main character), after which you'll head inside of the building to an auditorium. Inside you will get a cutscene, when you regain control of Aya you'll want to run up to the stage and interact with the girl in red that's there for another scene.
Our first fight of the game happens and it's mostly a tutorial fight. Combat in this game is pretty awesome, when you press the action button you will make a globe around Aya (your attack range). For right now all we can do is fire off a shot at the lady so do that, you'll be rewarded with the Heal power and the battle will start again.
Keep shooting and dodging the beams until you beat her. When you regain control of Aya follow Eve off stage and into the next area (go behind the red curtain to get to the new area, in front of the red curtain to get back to the auditorium). You'll find a large hole in the ground along with a chest nearby which is the same color as the ground. It's easy to miss this chest so I provided a picture below.
Loot in this game from some chests is not consistent from playthrough to playthrough. Chests that give new weapons are (mostly) the same but other chests which give you consumables seem to have a stock they rotate through which makes it more random. Keep this in mind when I list items from chests, it's what I got most often when I played the game. I will only list the chests that I believe are consistent from playthrough to playthrough.
Before you jump down the hole, if you'd like a full heal and some free items return to the entrance of Carnegie Hall and speak with the two cops and the Paramedic. One of the cops will give you +6 Ammo each time you speak with him until you get a total of 60 Ammo from him.
When you're ready to continue, jump down the hole and you will meet a young girl. The next room will be a long hallway with multiple locked doors, a cutscene will trigger in the middle of the hallway followed by a battle. After fighting the rat start going through doors in this area to find some items and story.
I recommend you search all the rooms for items, EXP and story elements, but all you need to progress the story is the Theater Key from the top left double door room. Search the chest in this room for an item along with the burned body for the key we need. You can also use the phone on the table to save your game.
Tip: Get into the habit of pressing the action button (X) around all objects. Just like most Ps1 games of the era, it isn't always obvious what you can and can't interact with. Sometimes items are hidden in the pre-rendered backgrounds.
Once you have the Theater Key you'll want to enter the door in the middle on the left side of the hallway. Inspect the diary in this room for some story elements and the Rehearse Key (pictured below). You need this key to open the door at the northern end of the hallway.
Before you proceed to the next area, return to the previous hallway with the two locked doors. The double doors on the right lead to a storage room, you can find some enemies in here and a chest at the southern end of the room. As for the door on the left, it will lead you to a small room with a blue chest. Near that blue chest is a cracked wall with a sword/shield hanging on it and next to that wall is a wardrobe.
Inspect the wardrobe to make a rat enemy spawn, once defeated inspect the wardrobe again to find a P220 pistol. Next open the chest (you will probably get an Offense +1) and then inspect the wall where the shield and sword is hanging to break down the wall. You'll find a chest inside with the N Protector armor.
Equip the new armor and weapon to Aya and use the +1 Offense you found on the new weapon to make it more powerful and to give us another inventory slot. When you're ready to continue with the main story go through the double doors at the far northern end of the hallway.
You will find Eve playing a piano inside of this room, approach her for another cutscene and a boss fight. Climb down the hole behind the piano when you're done and you'll find yourself in the sewers. Head north to the stairs and grab the chest under them, it has a M1911A1 inside which is a new pistol for Aya. Up the stairs you'll find two rats and a dead end, it will however show you the location of two chests downstairs which are hard to see otherwise.
When you go up the water canal you will get another scene with the young girl, grab the chests in the top right and left corners then the final chest next to our exit in the west. In the tunnel you will find a gate at the far end which has a control panel next to it. Inspect the control panel to open the gate and save your game.
Eve is found in the next room, after a short scene you'll have a boss battle against a mutant alligator. This fight can actually be pretty tough, you'll want to focus on the tail first and you'll have to time your attack volleys just right to do maximum damage. My advice is to wait until the boss spins and does the tail attack then unload on the tail while standing behind him. If you try and hit from the front, you'll do like 1/4th the amount of damage you could be doing.
Defeating this boss will complete Day 1.