Progression Server Spell Research Guide (Velious)
Spell Research allows you to make spells that you couldn't otherwise acquire or that would be otherwise extremely difficult to acquire. Until PoP it's one of the only ways to get a lot of the useful spells for some classes, like some Necromancer and Mage pets as well as many other spells for many other classes. PoP devalues the Tradeskill a little since you can buy all your spells in one place but it still has its uses.
As with all Tradeskills, for the first 21 points you will want to visit your Guildmaster and spend some practices.
Spell Research 1 - 21
Speak with your Guildmaster.
(Direct Route) Vial of Pure Water 21 - 54
All of the Vials of Pure Water that you make you will want to save for use in the future.
Empty Vial x 5
Gnomish Heat Source
Water Flask x 4
(Direct Route) Oil of Vitrol 54 - 102
Save all of these for making spells in the future!
Crystallized Sulfur
Gnomish Heat Source
Saltpeter
Vial of Pure Water
(Direct Route) Parchment Solution 102 - 144
Save all of these for making spells in the future!
Aqua Regia
Fire Emerald
Gnomish Heat Source
Vial of Pure Water
(Direct Route) Fine Parchment Solution 144 - 174
Save all of these for making spells in the future!
Aqua Regia
Fire Emerald
Gnomish Heat Source x 4
Gold Bar x 2
Vial of Pure Water x 2
(Direct Route) Vellum Parchment Solution 174 - 203
Save all of these for making spells in the future!
Aqua Regia
Gnomish Heat Source x 3
Gold Bar x 3
Platinum Bar
Vial of Pure Water
(Direct Route) Fine Vellum Parchment Solution 203 - 216
Save all of these for making spells in the future!
Aqua Regia
Fire Opal
Gnomish Heat Source x 2
Peridot
Platinum Bar
Vial of Muriatic Acid
Vial of Pure Water x 2
(Direct Route) Runic Parchment Solution 213 - 243
Save all of these for making spells in the future!
Aqua Regia
Gnomish Heat Source
Gold Bar
Platinum Bar
Star Ruby
Vial of Muriatic Acid
Vial of Pure Water x 2
Past 243 you will want to make any spells you can that will give you a skill up. A good way to level up Researching for little to no cost is make spells for anyone who needs it. As long as they supply the mats you got a free shot at a combine! Also there are quite a few different combines you can do with the researching hides that drop from mostly all of the humanoid creatures.